› 5a4o

X-ray diffraction
1.76Å resolution

Crystal structure of BPSL1147, a PC4 homolog from Burkholderia pseudomallei K96243 (orthorhombic crystal form)

Released:
DOI: 10.2210/pdb5a4o/pdb
PDB entry 5a4o coloured by chain, front view.
PDB entry 5a4o coloured by chain, side view.
PDB entry 5a4o coloured by chain, top view.
Source organism: Burkholderia pseudomallei K96243
Primary publication:
Structural analysis and knock-out of a Burkholderia pseudomallei homolog of the eukaryotic transcription coactivator PC4.
Werten S, Kohler C, Bayer NJ, Steinmetz I, Hinrichs W
Gene 577 140-7 (2016)
PMID: 26625975

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179095 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcriptional coactivator p15 (PC4) C-terminal domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 75 amino acids
Theoretical weight: 8.56 KDa
Source organism: Burkholderia pseudomallei K96243
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q63VU8 (Residues: 1-75; Coverage: 100%)
Gene name: BPSL1147
Sequence domains: Transcriptional Coactivator p15 (PC4)

Ligands and Environments

1 bound ligand:
Ligand CL 6 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.1
Spacegroup: P212121
Unit cell:
a: 38.374Å b: 50.149Å c: 63.533Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.196 0.191 0.241
Expression system: Escherichia coli BL21(DE3)

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Citations

1 review citation

Sub1/PC4, a multifaceted factor: from transcription to genome stability.
Garavís et al. (2017)
4 other articles