› 5a6f

Electron Microscopy
4.2Å resolution

Cryo-EM structure of the Slo2.2 Na-activated K channel

Released:
DOI: 10.2210/pdb5a6f/pdb
PDB entry 5a6f coloured by chain, front view.
PDB entry 5a6f coloured by chain, side view.
PDB entry 5a6f coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Cryo-electron microscopy structure of the Slo2.2 Na(+)-activated K(+) channel.
Hite RK, Yuan P, Li Z, Hsuing Y, Walz T, MacKinnon R
Nature 527 198-203 (2015)
PMID: 26436452
Related structures: EMD-3063

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-165426 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Potassium channel subfamily T member 1 Chain: C
Molecule details ›
Chain: C
Length: 700 amino acids
Theoretical weight: 79.32 KDa
Source organism: Gallus gallus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q8QFV0 (Residues: 351-1019; Coverage: 56%)
Gene names: KCNT1, SLACK
Sequence domains: Calcium-activated BK potassium channel alpha subunit
RCK2 ELABORATION OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1 Chain: D
Molecule details ›
Chain: D
Length: 43 amino acids
Theoretical weight: 3.68 KDa
Source organism: Gallus gallus
Expression system: Spodoptera frugiperda

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.2Å
Relevant EMDB volumes: EMD-3063
Expression system: Spodoptera frugiperda

Quick links

Citations

28 review citations

Unravelling biological macromolecules with cryo-electron microscopy.
Fernandez-Leiro et al. (2016)
27 more

1 mention without citation

Cryo-electron microscopy structure of the Slo2.2 Na(+)-activated K(+) channel.
Hite et al. (2015)