› 5axd

X-ray diffraction
1.6Å resolution

Crystal structure of mouse SAHH complexed with ribavirin

Released:
DOI: 10.2210/pdb5axd/pdb
PDB entry 5axd coloured by chain, front view.
PDB entry 5axd coloured by chain, side view.
PDB entry 5axd coloured by chain, top view.
Source organism: Mus musculus
Entry authors: Kusakabe Y, Ishihara M, Tanaka N

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156152 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenosylhomocysteinase Chains: A, C
Molecule details ›
Chains: A, C
Length: 432 amino acids
Theoretical weight: 47.75 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P50247 (Residues: 1-432; Coverage: 100%)
Gene name: Ahcy
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand NAD 2 x NAD
Ligand RBV 2 x RBV
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE AR-NE3A
Spacegroup: I222
Unit cell:
a: 100.58Å b: 104.612Å c: 177.007Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.159 0.158 0.18
Expression system: Escherichia coli

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