› 5b1q

X-ray diffraction
1.85Å resolution

Human herpesvirus 6B tegument protein U14

Released:
DOI: 10.2210/pdb5b1q/pdb
PDB entry 5b1q coloured by chain, front view.
PDB entry 5b1q coloured by chain, side view.
PDB entry 5b1q coloured by chain, top view.
Source organism: Human betaherpesvirus 6B
Primary publication:
Crystal Structure of Human Herpesvirus 6B Tegument Protein U14.
Wang B, Nishimura M, Tang H, Kawabata A, Mahmoud NF, Khanlari Z, Hamada D, Tsuruta H, Mori Y
PLoS Pathog 12 e1005594 (2016)
PMID: 27152739

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194377 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
U14 protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 459 amino acids
Theoretical weight: 52.67 KDa
Source organism: Human betaherpesvirus 6B
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q9WT50 (Residues: 2-458; Coverage: 76%)
Gene name: U14
Sequence domains: Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25)

Ligands and Environments

1 bound ligand:
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P21212
Unit cell:
a: 99.33Å b: 211.53Å c: 51.78Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.18 0.233
Expression system: Escherichia coli BL21

Quick links

Citations

1 review citation

Role of Viruses in the Pathogenesis of Multiple Sclerosis.
Tarlinton et al. (2020)
7 other articles

2 mentions without citation

Crystal Structure of Human Herpesvirus 6B Tegument Protein U14.
Wang et al. (2016)
1 more