› 5bni

X-ray diffraction
2.5Å resolution

Porcine CD38 complexed with complexed with a covalent intermediate, ribo-F-ribose-5'-phosphate

Released:
DOI: 10.2210/pdb5bni/pdb
PDB entry 5bni coloured by chain, front view.
PDB entry 5bni coloured by chain, side view.
PDB entry 5bni coloured by chain, top view.
Source organism: Sus scrofa
Primary publication:
Porcine CD38 exhibits prominent secondary NAD(+) cyclase activity.
Ting KY, Leung CF, Graeff RM, Lee HC, Hao Q, Kotaka M
Protein Sci 25 650-61 (2016)
PMID: 26660500

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-237260 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Uncharacterized protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 232 amino acids
Theoretical weight: 26.43 KDa
Source organism: Sus scrofa
Expression system: Komagataella pastoris
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand AVW 1 x AVW
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL13B1
Spacegroup: P21212
Unit cell:
a: 69.507Å b: 104.973Å c: 63.785Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.192 0.187 0.278
Expression system: Komagataella pastoris

Quick links

Citations

3 citation in other articles

Codonopsis pilosula Polysaccharides Alleviate Aβ 1-40-Induced PC12 Cells Energy Dysmetabolism via CD38/NAD+ Signaling Pathway.
Hu et al. (2021)
2 more

2 mentions without citation

Principles for computational design of binding antibodies.
Baran et al. (2017)
1 more