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› 5bvs

X-ray diffraction
2.2Å resolution

Linoleate-bound pFABP4

Released:
DOI: 10.2210/pdb5bvs/pdb
Model geometry
Fit model/data
PDB entry 5bvs coloured by chain, front view.
PDB entry 5bvs coloured by chain, side view.
PDB entry 5bvs coloured by chain, top view.
Source organism: Pygoscelis papua
Primary publication:
Structural basis for the ligand-binding specificity of fatty acid-binding proteins (pFABP4 and pFABP5) in gentoo penguin.
Lee CW, Kim JE, Do H, Kim RO, Lee SG, Park HH, Chang JH, Yim JH, Park H, Kim IC, Lee JH
Biochem Biophys Res Commun 465 12-8 (2015)
PMID: 26206084

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-102293 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein, adipocyte Chains: A, B
Molecule details ›
Chains: A, B
Length: 132 amino acids
Theoretical weight: 14.96 KDa
Source organism: Pygoscelis papua
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A0K0MJN3 (Residues: 1-132; Coverage: 100%)
Gene name: FABP4
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:
Ligand EIC 2 x EIC
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: PAL/PLS BEAMLINE 7A (6B, 6C1)
Spacegroup: P61
Unit cell:
a: 60.487Å b: 60.487Å c: 139.569Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.189 0.187 0.226
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Regulation of macrophage functions by FABP-mediated inflammatory and metabolic pathways.
Jin et al. (2021)
7 other articles