5bz2

X-ray diffraction
3.7Å resolution

CRYSTAL STRUCTURE OF THE SODIUM PROTON ANTIPORTER NAPA IN INWARD-FACING CONFORMATION

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-177946 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cation/H+ exchanger domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 386 amino acids
Theoretical weight: 40.31 KDa
Source organism: Thermus thermophilus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5SIA2 (Residues: 1-386; Coverage: 100%)
Gene name: TTHA1472
Sequence domains: Sodium/hydrogen exchanger family
Structure domains: Na+/H+ antiporter like fold

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I24
Spacegroup: C2221
Unit cell:
a: 77.71Å b: 84.64Å c: 201.78Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.294 0.29 0.328
Expression system: Escherichia coli BL21(DE3)