› 5bzc

X-ray diffraction
1.95Å resolution

Crystal structure of the murine CD44 hyaluronan binding domain complex with a small molecule

Released:
DOI: 10.2210/pdb5bzc/pdb
PDB entry 5bzc coloured by chain, front view.
PDB entry 5bzc coloured by chain, side view.
PDB entry 5bzc coloured by chain, top view.
Source organism: Mus musculus
Entry authors: Liu LK, Finzel BC

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147332 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CD44 antigen Chain: A
Molecule details ›
Chain: A
Length: 151 amino acids
Theoretical weight: 16.84 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P15379 (Residues: 22-171; Coverage: 20%)
Gene names: Cd44, Ly-24
Sequence domains: Extracellular link domain

Ligands and Environments

2 bound ligands:
Ligand 4WT 1 x 4WT
Ligand DMS 1 x DMS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 4.2.2
Spacegroup: P21
Unit cell:
a: 30.97Å b: 81.94Å c: 32.06Å
α: 90° β: 117.91° γ: 90°
R-values:
R R work R free
0.184 0.182 0.232
Expression system: Escherichia coli BL21(DE3)

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