› 5cca

X-ray diffraction
3.2Å resolution

Crystal structure of Mtb toxin

Released:
DOI: 10.2210/pdb5cca/pdb
Model geometry
Fit model/data
PDB entry 5cca coloured by chain, front view.
PDB entry 5cca coloured by chain, side view.
PDB entry 5cca coloured by chain, top view.
Source organism: Mycobacterium tuberculosis
Entry authors: Cascio D, Arbing M, de Serrano V, Eisenberg D, Miallau L, TB Structural Genomics Consortium (TBSGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo octamer
Assembly name:
PDBe Complex ID:
PDB-CPX-161627 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Endoribonuclease MazF3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 124 amino acids
Theoretical weight: 13.52 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli
UniProt:
  • Canonical: P9WIH9 (Residues: 1-103; Coverage: 100%)
Gene names: Rv1102c, mazF-mt6, mazF3
Sequence domains: PemK-like, MazF-like toxin of type II toxin-antitoxin system
Structure domains: SH3 type barrels.

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 24-ID-C
Spacegroup: P6422
Unit cell:
a: 105.555Å b: 105.555Å c: 142.417Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.3 0.3 0.302
Expression system: Escherichia coli

Quick links