5cmn

X-ray diffraction
3.6Å resolution

FLRT3 LRR domain in complex with LPHN3 Olfactomedin domain

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-190720 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Leucine-rich repeat transmembrane protein FLRT3 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 333 amino acids
Theoretical weight: 37.96 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q9NZU0 (Residues: 29-357; Coverage: 53%)
Gene names: FLRT3, KIAA1469, UNQ856/PRO1865
Sequence domains: Leucine rich repeat
Structure domains: Ribonuclease Inhibitor
Adhesion G protein-coupled receptor L3 Chains: E, F, G, H
Molecule details ›
Chains: E, F, G, H
Length: 261 amino acids
Theoretical weight: 30.01 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: Q9HAR2 (Residues: 132-392; Coverage: 18%)
Gene names: ADGRL3, KIAA0768, LEC3, LPHN3
Sequence domains: Olfactomedin-like domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-BM
Spacegroup: P43
Unit cell:
a: 102.268Å b: 102.268Å c: 419.23Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.195 0.262
Expression system: Trichoplusia ni