Function and Biology Details
Reaction catalysed:
Catalyzes the rearrangement of -S-S- bonds in proteins
Biochemical function:
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Protein disulfide-isomerase and Alpha-synuclein (preferred)
PDBe Complex ID:
PDB-CPX-153496 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Protein disulfide-isomerase
Molecule details ›
Chain: A
Length: 247 amino acids
Theoretical weight: 27.01 KDa
Source organism: Humicola insolens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Structure domains: Glutaredoxin
Length: 247 amino acids
Theoretical weight: 27.01 KDa
Source organism: Humicola insolens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P55059 (Residues: 228-469; Coverage: 50%)
Structure domains: Glutaredoxin
Alpha-synuclein
Molecule details ›
Chain: B
Length: 11 amino acids
Theoretical weight: 1.15 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 11 amino acids
Theoretical weight: 1.15 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P37840 (Residues: 31-41; Coverage: 8%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SPRING-8 BEAMLINE BL44XU
Spacegroup:
P212121
Expression systems:
- Escherichia coli BL21(DE3)
- Not provided
