› 5cwe

X-ray diffraction
2.39Å resolution

Structure of CYP107L2 from Streptomyces avermitilis with lauric acid

Released:
DOI: 10.2210/pdb5cwe/pdb
PDB entry 5cwe coloured by chain, front view.
PDB entry 5cwe coloured by chain, side view.
PDB entry 5cwe coloured by chain, top view.
Source organism: Streptomyces avermitilis MA-4680 = NBRC 14893
Entry authors: Pham T-V, Han S-H, Kim J-H, Kim D-H, Kang L-W

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182671 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytochrome P450 hydroxylase Chains: A, B
Molecule details ›
Chains: A, B
Length: 393 amino acids
Theoretical weight: 43.18 KDa
Source organism: Streptomyces avermitilis MA-4680 = NBRC 14893
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q82LM3 (Residues: 1-393; Coverage: 100%)
Gene names: SAVERM_1987, cyp8
Sequence domains: Cytochrome P450
Structure domains: Cytochrome P450

Ligands and Environments

4 bound ligands:
Ligand SO4 2 x SO4
Ligand DAO 2 x DAO
Ligand HEM 2 x HEM
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: P21
Unit cell:
a: 64.08Å b: 118.371Å c: 66.039Å
α: 90° β: 105.51° γ: 90°
R-values:
R R work R free
0.23 0.226 0.301
Expression system: Escherichia coli BL21(DE3)

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