› 5cyw

X-ray diffraction
2Å resolution

Crystal Structure of Vaccinia Virus C7

Released:
DOI: 10.2210/pdb5cyw/pdb
PDB entry 5cyw coloured by chain, front view.
PDB entry 5cyw coloured by chain, side view.
PDB entry 5cyw coloured by chain, top view.
Source organism: Vaccinia virus Ankara
Primary publication:
Structural basis for antagonizing a host restriction factor by C7 family of poxvirus host-range proteins.
Meng X, Krumm B, Li Y, Deng J, Xiang Y
Proc Natl Acad Sci U S A 112 14858-63 (2015)
PMID: 26578811

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo trimer
Assembly name:
PDBe Complex ID:
PDB-CPX-159486 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Interferon antagonist OPG027 Chain: B
Molecule details ›
Chain: B
Length: 152 amino acids
Theoretical weight: 18.22 KDa
Source organism: Vaccinia virus Ankara
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P68598 (Residues: 1-150; Coverage: 100%)
Gene names: C7L, MVA018L, OPG027
Sequence domains: Poxvirus C7/F8A protein

Ligands and Environments

1 bound ligand:
Ligand GOL 2 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P213
Unit cell:
a: 100.653Å b: 100.653Å c: 100.653Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.155 0.153 0.182
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

Germline predisposition in myeloid neoplasms: Unique genetic and clinical features of GATA2 deficiency and SAMD9/SAMD9L syndromes.
Sahoo et al. (2020)
3 more

5 mentions without citation

Self-association of a highly charged arginine-rich cell-penetrating peptide.
Tesei et al. (2017)
4 more