Function and Biology Details
Reactions catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Endonucleolytic cleavage to 5'-phosphomonoester.
dUTP + H(2)O = dUMP + diphosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Integrase (preferred)
PDBe Complex ID:
PDB-CPX-136837 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Integrase
Molecule details ›
Chains: A, B, C, D
Length: 169 amino acids
Theoretical weight: 19.31 KDa
Source organism: Mouse mammary tumor virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Integrase core domain
Structure domains: Ribonuclease H-like superfamily/Ribonuclease H
Length: 169 amino acids
Theoretical weight: 19.31 KDa
Source organism: Mouse mammary tumor virus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P03365 (Residues: 1487-1648; Coverage: 9%)
Sequence domains: Integrase core domain
Structure domains: Ribonuclease H-like superfamily/Ribonuclease H
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
ESRF BEAMLINE BM14
Spacegroup:
P1
Expression system: Escherichia coli BL21(DE3)
