› 5dil

X-ray diffraction
2.01Å resolution

Crystal structure of the effector domain of the NS1 protein from influenza virus B

Released:
DOI: 10.2210/pdb5dil/pdb
PDB entry 5dil coloured by chain, front view.
PDB entry 5dil coloured by chain, side view.
PDB entry 5dil coloured by chain, top view.
Source organism: Influenza B virus (B/Singapore/DSO_090134/2004)
Primary publication:
A Second RNA-Binding Site in the NS1 Protein of Influenza B Virus.
Ma LC, Guan R, Hamilton K, Aramini JM, Mao L, Wang S, Krug RM, Montelione GT
Structure 24 1562-72 (2016)
PMID: 27545620

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-197839 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Non-structural protein 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 141 amino acids
Theoretical weight: 16.01 KDa
Source organism: Influenza B virus (B/Singapore/DSO_090134/2004)
Expression system: Escherichia coli
UniProt:
  • Canonical: X2C382 (Residues: 141-281; Coverage: 50%)
Gene name: NS1
Sequence domains: Influenza B non-structural protein (NS1)

Ligands and Environments

1 bound ligand:
Ligand IOD 13 x IOD
1 modified residue:
Ligand MSE 2 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: P1
Unit cell:
a: 34.689Å b: 41.666Å c: 49.681Å
α: 68.72° β: 82.83° γ: 78.12°
R-values:
R R work R free
0.199 0.194 0.242
Expression system: Escherichia coli

Quick links

Citations

5 citation in other articles

Influenza Virus Mounts a Two-Pronged Attack on Host RNA Polymerase II Transcription.
Bauer et al. (2018)
4 more

3 mentions without citation

A Second RNA-Binding Site in the NS1 Protein of Influenza B Virus.
Ma et al. (2016)
2 more