› 5dl2

X-ray diffraction
3.5Å resolution

Crystal Structure of RopB

Released:
DOI: 10.2210/pdb5dl2/pdb
PDB entry 5dl2 coloured by chain, front view.
PDB entry 5dl2 coloured by chain, side view.
PDB entry 5dl2 coloured by chain, top view.
Source organism: Streptococcus pyogenes MGAS10870
Primary publication:
Structural and functional analysis of RopB: a major virulence regulator in Streptococcus pyogenes.
Makthal N, Gavagan M, Do H, Olsen RJ, Musser JM, Kumaraswami M
Mol Microbiol 99 1119-33 (2016)
PMID: 26714274

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-112522 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH-type transcriptional regulator Rgg C-terminal domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 234 amino acids
Theoretical weight: 27.98 KDa
Source organism: Streptococcus pyogenes MGAS10870
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: D3KVD8 (Residues: 55-280; Coverage: 81%)
Gene name: rgg
Sequence domains: HTH-type transcriptional regulator Rgg, C-terminal domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P3212
Unit cell:
a: 94.06Å b: 94.06Å c: 178.27Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.28 0.276 0.313
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Genetic and Structural Analyses of RRNPP Intercellular Peptide Signaling of Gram-Positive Bacteria.
Neiditch et al. (2017)
2 more

2 mentions without citation

Structural Mechanisms of Peptide Recognition and Allosteric Modulation of Gene Regulation by the RRNPP Family of Quorum-Sensing Regulators.
Do et al. (2016)
1 more