Function and Biology Details
Reactions catalysed:
ATP + RNA(n) = diphosphate + RNA(n+1)
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
ADP-D-ribose 1''-phosphate + H(2)O = ADP-D-ribose + phosphate
NTP + H(2)O = NDP + phosphate
A 5'-triphospho-[mRNA] + H(2)O = a 5'-diphospho-[mRNA] + phosphate
ATP + H(2)O = ADP + phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-140120 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ras GTPase-activating protein-binding protein 2
Molecule details ›
Chain: A
Length: 142 amino acids
Theoretical weight: 16.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Nuclear transport factor 2 (NTF2) domain
Structure domains: Nuclear Transport Factor 2; Chain: A,
Length: 142 amino acids
Theoretical weight: 16.14 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q9UN86 (Residues: 1-139; Coverage: 29%)
Sequence domains: Nuclear transport factor 2 (NTF2) domain
Structure domains: Nuclear Transport Factor 2; Chain: A,
Non-structural protein 3
Molecule details ›
Chain: B
Length: 8 amino acids
Theoretical weight: 943 Da
Source organism: Semliki Forest virus
Expression system: Not provided
UniProt:
Length: 8 amino acids
Theoretical weight: 943 Da
Source organism: Semliki Forest virus
Expression system: Not provided
UniProt:
- Canonical: P08411 (Residues: 1785-1792; Coverage: 0%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID23-2
Spacegroup:
R32
Expression systems:
- Escherichia coli BL21(DE3)
- Not provided
