› 5dse

X-ray diffraction
2.9Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-183172 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tetratricopeptide repeat protein 7B Chains: A, C
Molecule details ›
Chains: A, C
Length: 837 amino acids
Theoretical weight: 93.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q86TV6 (Residues: 7-843; Coverage: 99%)
Gene names: TTC7B, TTC7L1
Sequence domains:
Hyccin Chains: B, D
Molecule details ›
Chains: B, D
Length: 312 amino acids
Theoretical weight: 34.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9BYI3 (Residues: 2-308; Coverage: 59%)
Gene names: DRCTNNB1A, FAM126A, HYCC1
Sequence domains: Hyccin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 24-ID-E
Spacegroup: P212121
Unit cell:
a: 71.779Å b: 168.068Å c: 239.671Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.213 0.212 0.242
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

15 review citations

Understanding phosphoinositides: rare, dynamic, and essential membrane phospholipids.
Dickson et al. (2019)
14 more

5 mentions without citation

The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane.
Baskin et al. (2016)
4 more