› 5e53

X-ray diffraction
2.5Å resolution

Crystal structure of chicken CNTN1 FN1-FN3 domains

Released:
DOI: 10.2210/pdb5e53/pdb
PDB entry 5e53 coloured by chain, front view.
PDB entry 5e53 coloured by chain, side view.
PDB entry 5e53 coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Structural Basis for Interactions Between Contactin Family Members and Protein-tyrosine Phosphatase Receptor Type G in Neural Tissues.
Nikolaienko RM, Hammel M, Dubreuil V, Zalmai R, Hall DR, Mehzabeen N, Karuppan SJ, Harroch S, Stella SL, Bouyain S
J Biol Chem 291 21335-21349 (2016)
PMID: 27539848

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147092 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Contactin-1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 301 amino acids
Theoretical weight: 33.55 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P14781 (Residues: 593-893; Coverage: 30%)
Gene name: CNTN1
Sequence domains: Fibronectin type III domain

Ligands and Environments

1 bound ligand:
Ligand IMD 15 x IMD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P21
Unit cell:
a: 87.484Å b: 49.871Å c: 163.302Å
α: 90° β: 97.12° γ: 90°
R-values:
R R work R free
0.207 0.205 0.247
Expression system: Escherichia coli BL21(DE3)

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Citations

9 review citations

Contactins in the central nervous system: role in health and disease.
Chatterjee et al. (2019)
8 more

3 mentions without citation

Conserved and Diverse Traits of Adhesion Devices from Siphoviridae Recognizing Proteinaceous or Saccharidic Receptors.
Goulet et al. (2020)
2 more