Function and Biology Details
Reaction catalysed:
Guanosine 3',5'-cyclic phosphate + H(2)O = guanosine 5'-phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
3',5'-cyclic phosphodiesterase (preferred)
PDBe Complex ID:
PDB-CPX-129173 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
Molecule details ›
Chains: A, C
Length: 149 amino acids
Theoretical weight: 17.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: GMP-PDE, delta subunit
Structure domains: GMP phosphodiesterase, delta subunit
Length: 149 amino acids
Theoretical weight: 17.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
O43924 (Residues: 2-150; Coverage: 99%)
Sequence domains: GMP-PDE, delta subunit
Structure domains: GMP phosphodiesterase, delta subunit
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'
Molecule details ›
Chains: D, E
Length: 5 amino acids
Theoretical weight: 582 Da
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Length: 5 amino acids
Theoretical weight: 582 Da
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P51160 (Residues: 851-855; Coverage: 1%)
