› 5ete

X-ray diffraction
2.1Å resolution

Structure of pathogen-related yeast protein, Pry1 in complex with a competitive inhibitor of cholesterol binding

Released:
DOI: 10.2210/pdb5ete/pdb
PDB entry 5ete coloured by chain, front view.
PDB entry 5ete coloured by chain, side view.
PDB entry 5ete coloured by chain, top view.
Source organism: Saccharomyces cerevisiae YJM1434
Primary publication:
Structural and functional characterization of the CAP domain of pathogen-related yeast 1 (Pry1) protein.
Darwiche R, Kelleher A, Hudspeth EM, Schneiter R, Asojo OA
Sci Rep 6 28838 (2016)
PMID: 27344972

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-165615 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pry1p Chain: A
Molecule details ›
Chain: A
Length: 149 amino acids
Theoretical weight: 15.9 KDa
Source organism: Saccharomyces cerevisiae YJM1434
Expression system: Pichia
Structure domains: CAP

Ligands and Environments

1 bound ligand:
Ligand DIO 4 x DIO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-E+ SUPERBRIGHT
Spacegroup: P6222
Unit cell:
a: 124.74Å b: 124.74Å c: 59.06Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.168 0.167 0.19
Expression system: Pichia

Quick links

Citations

4 review citations

Emerging Insights into the Functions of Pathogenesis-Related Protein 1.
Breen et al. (2017)
3 more

5 mentions without citation

Structural and functional characterization of the CAP domain of pathogen-related yeast 1 (Pry1) protein.
Darwiche et al. (2016)
4 more