› 5ez5

X-ray diffraction
2.4Å resolution

Crystal structure of active Rab11A (S20V) in complex with GTP

Released:
DOI: 10.2210/pdb5ez5/pdb
PDB entry 5ez5 coloured by chain, front view.
PDB entry 5ez5 coloured by chain, side view.
PDB entry 5ez5 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Shin Y-C, Yoon JH, Park HH

Function and Biology Details

Reaction catalysed: 
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158629 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras-related protein Rab-11A Chains: A, B
Molecule details ›
Chains: A, B
Length: 168 amino acids
Theoretical weight: 18.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P62491 (Residues: 8-175; Coverage: 78%)
Gene names: RAB11, RAB11A
Sequence domains: Ras family
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
Ligand MG 2 x MG
Ligand GTP 2 x GTP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 5C (4A)
Spacegroup: I4
Unit cell:
a: 74.111Å b: 74.111Å c: 149.444Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.24 0.237 0.304
Expression system: Escherichia coli

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