5f34

X-ray diffraction
3.28Å resolution

Crystal structure of membrane associated PatA from Mycobacterium smegmatis in complex with S-hexadecyl Coenzyme A - P21 space group

Released:

Function and Biology Details

Reaction catalysed:
An acyl-CoA + 2,6-di-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol = CoA + 2-O-(6-O-acyl-alpha-D-mannosyl)-6-O-alpha-D-mannosyl-1-phosphatidyl-1D-myo-inositol
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-106349 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphatidylinositol mannoside acyltransferase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 308 amino acids
Theoretical weight: 34.3 KDa
Source organism: Mycolicibacterium smegmatis MC2 155
Expression system: Mycolicibacterium smegmatis MC2 155
UniProt:
  • Canonical: A0QWG5 (Residues: 13-304; Coverage: 96%)
Gene names: MSMEG_2934, MSMEI_2860, patA
Sequence domains: Bacterial lipid A biosynthesis acyltransferase

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P21
Unit cell:
a: 81.08Å b: 80.27Å c: 97.38Å
α: 90° β: 110.92° γ: 90°
R-values:
R R work R free
0.266 0.264 0.306
Expression system: Mycolicibacterium smegmatis MC2 155