› 5f7h

X-ray diffraction
2.5Å resolution

Human T-cell immunoglobulin and mucin domain protein 4 (hTIM-4) complex with phosphoserine

Released:
DOI: 10.2210/pdb5f7h/pdb
PDB entry 5f7h coloured by chain, front view.
PDB entry 5f7h coloured by chain, side view.
PDB entry 5f7h coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structures of human TIM members: Ebolavirus entry-enhancing receptors
Wang H, Qi JX, Liu NN
Chin. Sci. Bull. 60 3438-3453 (2015)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-188525 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
T-cell immunoglobulin and mucin domain-containing protein 4 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 113 amino acids
Theoretical weight: 12.67 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96H15 (Residues: 24-134; Coverage: 31%)
Gene names: TIM4, TIMD4
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
Ligand CA 6 x CA
Ligand SEP 6 x SEP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: C2
Unit cell:
a: 212.444Å b: 65.034Å c: 68.851Å
α: 90° β: 108.55° γ: 90°
R-values:
R R work R free
0.213 0.21 0.278
Expression system: Escherichia coli

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