› 5frf

Solution NMR

Solution structure of reduced and zinc-bound RsrA

Released:
DOI: 10.2210/pdb5frf/pdb
PDB entry 5frf coloured by chain, ensemble of 10 models, front view.
PDB entry 5frf coloured by chain, ensemble of 10 models, side view.
PDB entry 5frf coloured by chain, ensemble of 10 models, top view.
Source organism: Streptomyces coelicolor
Primary publication:
The anti-sigma factor RsrA responds to oxidative stress by reburying its hydrophobic core.
Rajasekar KV, Zdanowski K, Yan J, Hopper JT, Francis ML, Seepersad C, Sharp C, Pecqueur L, Werner JM, Robinson CV, Mohammed S, Potts JR, Kleanthous C
Nat Commun 7 12194 (2016)
PMID: 27432510

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181335 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Anti-sigma factor RsrA Chain: A
Molecule details ›
Chain: A
Length: 108 amino acids
Theoretical weight: 11.84 KDa
Source organism: Streptomyces coelicolor
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q7AKG8 (Residues: 1-105; Coverage: 100%)
Gene names: SCO5217, rsrA
Sequence domains: Putative zinc-finger

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 72%
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

Themes and variations in gene regulation by extracytoplasmic function (ECF) sigma factors.
Sineva et al. (2017)
3 more

1 mention without citation

The anti-sigma factor RsrA responds to oxidative stress by reburying its hydrophobic core.
Rajasekar et al. (2016)