› 5fv0

X-ray diffraction
2.91Å resolution

The cytoplasmic domain of EssC

Released:
DOI: 10.2210/pdb5fv0/pdb
PDB entry 5fv0 coloured by chain, front view.
PDB entry 5fv0 coloured by chain, side view.
PDB entry 5fv0 coloured by chain, top view.
Source organism: Geobacillus thermodenitrificans
Primary publication:
EssC: domain structures inform on the elusive translocation channel in the Type VII secretion system.
Zoltner M, Ng WM, Money JJ, Fyfe PK, Kneuper H, Palmer T, Hunter WN
Biochem J 473 1941-52 (2016)
PMID: 27130157

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-107337 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ESX secretion system protein EccC Chains: A, B
Molecule details ›
Chains: A, B
Length: 517 amino acids
Theoretical weight: 58.89 KDa
Source organism: Geobacillus thermodenitrificans
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A4IKE7 (Residues: 966-1479; Coverage: 35%)
Gene names: GTNG_0419, eccC, essC
Sequence domains: FtsK/SpoIIIE family

Ligands and Environments

3 bound ligands:
Ligand ONA 1 x ONA
Ligand 1PE 1 x 1PE
Ligand ATP 1 x ATP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: I222
Unit cell:
a: 85.917Å b: 152.372Å c: 207.205Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.262 0.261 0.275
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

The Enigmatic Esx Proteins: Looking Beyond Mycobacteria.
Unnikrishnan et al. (2017)
1 more

3 mentions without citation

Interbacterial competition mediated by the type VIIb secretion system.
Boardman et al. (2023)
2 more