› 5fxu

X-ray diffraction
2.28Å resolution

Crystal Structure of Puumala virus Gn glycoprotein ectodomain

Released:
DOI: 10.2210/pdb5fxu/pdb
PDB entry 5fxu coloured by chain, front view.
PDB entry 5fxu coloured by chain, side view.
PDB entry 5fxu coloured by chain, top view.
Source organism: Puumala orthohantavirus
Primary publication:
A Molecular-Level Account of the Antigenic Hantaviral Surface.
Li S, Rissanen I, Zeltina A, Hepojoki J, Raghwani J, Harlos K, Pybus OG, Huiskonen JT, Bowden TA
Cell Rep 15 959-967 (2016)
PMID: 27117403

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194363 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (4 distinct):
Glycoprotein Chains: A, B
Molecule details ›
Chains: A, B
Length: 367 amino acids
Theoretical weight: 40.06 KDa
Source organism: Puumala orthohantavirus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q9WJ31 (Residues: 29-383; Coverage: 31%)
Gene name: gpc
Sequence domains: Hantavirus glycoprotein Gn, head

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I03
Spacegroup: P1
Unit cell:
a: 51.57Å b: 66.79Å c: 77.35Å
α: 107.3° β: 93.55° γ: 100.94°
R-values:
R R work R free
0.19 0.189 0.219
Expression system: Homo sapiens

Quick links

Citations

5 review citations

The HIV-1 envelope glycoprotein structure: nailing down a moving target.
Ward et al. (2017)
4 more

10 mentions without citation

Recent Advances in Bunyavirus Glycoprotein Research: Precursor Processing, Receptor Binding and Structure.
Hulswit et al. (2021)
9 more