› 5gib

X-ray diffraction
2.7Å resolution

Succinic acid bound trypsin crystallized as dimer

Released:
DOI: 10.2210/pdb5gib/pdb
PDB entry 5gib coloured by chain, front view.
PDB entry 5gib coloured by chain, side view.
PDB entry 5gib coloured by chain, top view.
Source organism: Bos taurus
Entry authors: Kutumbarao NHV, Manohar R, KarthiK L, Malathy P, Gunasekaran K, Velmurugan D

Function and Biology Details

Reaction catalysed: 
Preferential cleavage: Arg-|-, Lys-|-.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133319 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine protease 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 223 amino acids
Theoretical weight: 23.32 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00760 (Residues: 24-246; Coverage: 97%)
Gene names: PRSS1, TRP1, TRY1, TRYP1
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases

Ligands and Environments

2 bound ligands:
Ligand SIN 1 x SIN
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR
Spacegroup: P212121
Unit cell:
a: 53.29Å b: 58.26Å c: 136.47Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.235 0.229 0.286

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