› 5gr7

X-ray diffraction
2.4Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
PDBe Complex ID:
PDB-CPX-125662 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
H-2 class I histocompatibility antigen, K-D alpha chain Chain: A
Molecule details ›
Chain: A
Length: 274 amino acids
Theoretical weight: 32 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P01902 (Residues: 22-295; Coverage: 79%)
Gene names: H2-K, H2-K1
Sequence domains:
Structure domains:
Beta-2-microglobulin Chain: B
Molecule details ›
Chain: B
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
Spike protein S1 Chain: C
Molecule details ›
Chain: C
Length: 9 amino acids
Theoretical weight: 1.09 KDa
Source organism: Middle East respiratory syndrome-related coronavirus
Expression system: Not provided
UniProt:
  • Canonical: K9N5Q8 (Residues: 292-300; Coverage: 1%)
Gene names: 3, S

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P212121
Unit cell:
a: 50.006Å b: 74.644Å c: 121.129Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.201 0.257
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

11 review citations

Vaccines for SARS-CoV-2: Lessons from Other Coronavirus Strains.
Padron-Regalado E. (2020)
10 more

2 mentions without citation

Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats.
Lu et al. (2019)
1 more