› 5gw0

X-ray diffraction
3.3Å resolution

Crystal structure of SNX16 PX-Coiled coil

Released:
DOI: 10.2210/pdb5gw0/pdb
PDB entry 5gw0 coloured by chain, front view.
PDB entry 5gw0 coloured by chain, side view.
PDB entry 5gw0 coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
SNX16 Regulates the Recycling of E-Cadherin through a Unique Mechanism of Coordinated Membrane and Cargo Binding.
Xu J, Zhang L, Ye Y, Shan Y, Wan C, Wang J, Pei D, Shu X, Liu J
Structure 25 1251-1263.e5 (2017)
PMID: 28712807

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157634 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sorting nexin-16 Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 179 amino acids
Theoretical weight: 21.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P57768 (Residues: 100-278; Coverage: 52%)
Gene name: SNX16
Sequence domains: PX domain
Structure domains: Phox-like domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 18 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P21
Unit cell:
a: 70.38Å b: 196.78Å c: 72.96Å
α: 90° β: 111.75° γ: 90°
R-values:
R R work R free
0.239 0.236 0.288
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Sorting Nexins in Protein Homeostasis.
Hanley et al. (2020)
1 more

3 mentions without citation

Higher-order assembly of Sorting Nexin 16 controls tubulation and distribution of neuronal endosomes.
Wang et al. (2019)
2 more