› 5h1d

X-ray diffraction
1.49Å resolution

Crystal structure of C-terminal of RhoGDI2

Released:
DOI: 10.2210/pdb5h1d/pdb
PDB entry 5h1d coloured by chain, front view.
PDB entry 5h1d coloured by chain, side view.
PDB entry 5h1d coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
NMR characterization of weak interactions between RhoGDI2 and fragment screening hits.
Liu J, Gao J, Li F, Ma R, Wei Q, Wang A, Wu J, Ruan K
Biochim Biophys Acta Gen Subj 1861 3061-3070 (2017)
PMID: 27721047

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-156570 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rho GDP-dissociation inhibitor 2 Chain: A
Molecule details ›
Chain: A
Length: 143 amino acids
Theoretical weight: 16.43 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'
UniProt:
  • Canonical: P52566 (Residues: 61-201; Coverage: 70%)
Gene names: ARHGDIB, GDIA2, GDID4, RAP1GN1
Sequence domains: RHO protein GDP dissociation inhibitor
Structure domains: Coagulation Factor XIII, subunit A, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: P43212
Unit cell:
a: 55.02Å b: 55.02Å c: 96.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.156 0.154 0.204
Expression system: Escherichia coli 'BL21-Gold(DE3)pLysS AG'

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Citations

1 review citation

Paramagnetic Chemical Probes for Studying Biological Macromolecules.
Miao et al. (2022)
5 other articles

1 mention without citation

Cannabinoid receptor interacting protein 1a interacts with myristoylated Gαi N terminus via a unique gapped β-barrel structure.
Booth et al. (2021)