5h1l

X-ray diffraction
2.1Å resolution

Crystal structure of WD40 repeat domains of Gemin5 in complex with 7-nt U4 snRNA fragment

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-186251 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Gem-associated protein 5 Chain: A
Molecule details ›
Chain: A
Length: 734 amino acids
Theoretical weight: 81.43 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q8TEQ6 (Residues: 1-726; Coverage: 48%)
Gene name: GEMIN5
Sequence domains:
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase
U4 snRNA (5'-R(*AP*UP*UP*UP*UP*UP*G)-3') Chain: B
Molecule details ›
Chain: B
Length: 7 nucleotides
Theoretical weight: 2.16 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL18U1
Spacegroup: P21
Unit cell:
a: 59.535Å b: 124.79Å c: 61.016Å
α: 90° β: 117.97° γ: 90°
R-values:
R R work R free
0.197 0.195 0.241
Expression systems:
  • Spodoptera frugiperda
  • Not provided