› 5h2q

X-ray diffraction
1.66Å resolution

Crystal structure of T brucei phosphodiesterase B2 bound to compound 13e

Released:
DOI: 10.2210/pdb5h2q/pdb
PDB entry 5h2q coloured by chain, front view.
PDB entry 5h2q coloured by chain, side view.
PDB entry 5h2q coloured by chain, top view.
Source organism: Trypanosoma brucei brucei TREU927
Entry author: Noble CG

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174418 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphodiesterase Chains: A, B
Molecule details ›
Chains: A, B
Length: 337 amino acids
Theoretical weight: 38.5 KDa
Source organism: Trypanosoma brucei brucei TREU927
UniProt:
  • Canonical: Q38F42 (Residues: 586-918; Coverage: 36%)
Gene name: Tb09.160.3630
Sequence domains: 3'5'-cyclic nucleotide phosphodiesterase
Structure domains: 3'5'-cyclic nucleotide phosphodiesterase, catalytic domain

Ligands and Environments

3 bound ligands:
Ligand ZN 2 x ZN
Ligand MG 2 x MG
Ligand LLI 2 x LLI
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: P3121
Unit cell:
a: 97.21Å b: 97.21Å c: 120.44Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.174 0.172 0.2

Quick links