› 5h36

X-ray diffraction
3.41Å resolution

Crystal structures of the TRIC trimeric intracellular cation channel orthologue from Rhodobacter sphaeroides

Released:
DOI: 10.2210/pdb5h36/pdb
PDB entry 5h36 coloured by chain, front view.
PDB entry 5h36 coloured by chain, side view.
PDB entry 5h36 coloured by chain, top view.
Source organism: Cereibacter sphaeroides 2.4.1
Primary publication:
Crystal structures of the TRIC trimeric intracellular cation channel orthologues.
Kasuya G, Hiraizumi M, Maturana AD, Kumazaki K, Fujiwara Y, Liu K, Nakada-Nakura Y, Iwata S, Tsukada K, Komori T, Uemura S, Goto Y, Nakane T, Takemoto M, Kato HE, Yamashita K, Wada M, Ito K, Ishitani R, Hattori M, Nureki O
Cell Res 26 1288-1301 (2016)
PMID: 27909292

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-174535 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glycine transporter domain-containing protein Chains: A, E
Molecule details ›
Chains: A, E
Length: 215 amino acids
Theoretical weight: 22.78 KDa
Source organism: Cereibacter sphaeroides 2.4.1
Expression system: Escherichia coli
UniProt:
  • Canonical: Q3HKN0 (Residues: 1-204; Coverage: 96%)
Gene name: RSP_3856
Sequence domains: Glycine transporter

Ligands and Environments

1 bound ligand:
Ligand PX4 2 x PX4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: R3
Unit cell:
a: 156.01Å b: 156.01Å c: 82.37Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.263 0.247 0.273
Expression system: Escherichia coli

Quick links

Citations

2 review citations

TRIC-A regulates intracellular Ca2+ homeostasis in cardiomyocytes.
Zhou et al. (2021)
1 more

3 mentions without citation

Crystal structures of the TRIC trimeric intracellular cation channel orthologues.
Kasuya et al. (2016)
2 more