› 5h4s

X-ray diffraction
1.8Å resolution

Crystal structure of a rhamnose-binding lectin SUL-I from the toxopneustid sea urchin Toxopneustes pileolus

Released:
DOI: 10.2210/pdb5h4s/pdb
PDB entry 5h4s coloured by chain, front view.
PDB entry 5h4s coloured by chain, side view.
PDB entry 5h4s coloured by chain, top view.
Source organism: Toxopneustes pileolus
Primary publication:
Carbohydrate recognition by the rhamnose-binding lectin SUL-I with a novel three-domain structure isolated from the venom of globiferous pedicellariae of the flower sea urchin Toxopneustes pileolus.
Hatakeyama T, Ichise A, Unno H, Goda S, Oda T, Tateno H, Hirabayashi J, Sakai H, Nakagawa H
Protein Sci 26 1574-1583 (2017)
PMID: 28470711

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-100693 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SUEL-type lectin domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 284 amino acids
Theoretical weight: 30.52 KDa
Source organism: Toxopneustes pileolus
Expression system: Escherichia coli
UniProt:
  • Canonical: A0A090BWT0 (Residues: 25-308; Coverage: 100%)
Gene name: SUL-1
Sequence domains: Galactose binding lectin domain

Ligands and Environments

2 bound ligands:
Ligand RAM 3 x RAM
Ligand PO4 1 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: C2
Unit cell:
a: 101.76Å b: 44.21Å c: 71.84Å
α: 90° β: 124.08° γ: 90°
R-values:
R R work R free
0.159 0.156 0.205
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Structural Diversities of Lectins Binding to the Glycosphingolipid Gb3.
Siukstaite et al. (2021)
1 more

2 mentions without citation

Functional Diversity of Novel Lectins with Unique Structural Features in Marine Animals.
Hatakeyama et al. (2023)
1 more