› 5hb1

X-ray diffraction
4.01Å resolution

Crystal structure of Chaetomium thermophilum Nup170 SOL

Released:
DOI: 10.2210/pdb5hb1/pdb
PDB entry 5hb1 coloured by chain, front view.
PDB entry 5hb1 coloured by chain, side view.
PDB entry 5hb1 coloured by chain, top view.
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Primary publication:
Architecture of the symmetric core of the nuclear pore.
Lin DH, Stuwe T, Schilbach S, Rundlet EJ, Perriches T, Mobbs G, Fan Y, Thierbach K, Huber FM, Collins LN, Davenport AM, Jeon YE, Hoelz A
Science 352 aaf1015 (2016)
PMID: 27081075

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-124032 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoporin NUP170 Chain: A
Molecule details ›
Chain: A
Length: 830 amino acids
Theoretical weight: 92.26 KDa
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Expression system: Escherichia coli
UniProt:
  • Canonical: G0S7B6 (Residues: 575-1403; Coverage: 59%)
Gene names: CTHT_0036270, NUP170
Sequence domains: Non-repetitive/WGA-negative nucleoporin C-terminal

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P21212
Unit cell:
a: 96.07Å b: 138.62Å c: 89.28Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.309 0.304 0.352
Expression system: Escherichia coli

Quick links

Citations

40 review citations

The nuclear pore complex: understanding its function through structural insight.
Beck et al. (2017)
39 more

3 mentions without citation

The Structure of the Nuclear Pore Complex (An Update).
Lin et al. (2019)
2 more