› 5hb8

X-ray diffraction
1.7Å resolution

Crystal structure of Chaetomium thermophilum Nup53 RRM (space group P3121)

Released:
DOI: 10.2210/pdb5hb8/pdb
PDB entry 5hb8 coloured by chain, front view.
PDB entry 5hb8 coloured by chain, side view.
PDB entry 5hb8 coloured by chain, top view.
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Primary publication:
Architecture of the symmetric core of the nuclear pore.
Lin DH, Stuwe T, Schilbach S, Rundlet EJ, Perriches T, Mobbs G, Fan Y, Thierbach K, Huber FM, Collins LN, Davenport AM, Jeon YE, Hoelz A
Science 352 aaf1015 (2016)
PMID: 27081075

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-123959 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleoporin NUP53 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 125 amino acids
Theoretical weight: 14.34 KDa
Source organism: Chaetomium thermophilum var. thermophilum DSM 1495
Expression system: Escherichia coli
UniProt:
  • Canonical: G0S156 (Residues: 133-253; Coverage: 28%)
Gene names: CTHT_0012410, NUP53

Ligands and Environments

2 bound ligands:
Ligand SIN 6 x SIN
Ligand GOL 5 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL12-2
Spacegroup: P3121
Unit cell:
a: 94.66Å b: 94.66Å c: 115.51Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.164 0.163 0.21
Expression system: Escherichia coli

Quick links

Citations

41 review citations

The nuclear pore complex: understanding its function through structural insight.
Beck et al. (2017)
40 more

2 mentions without citation

Architecture of the symmetric core of the nuclear pore.
Lin et al. (2016)
1 more