› 5hl3

X-ray diffraction
1.4Å resolution

Crystal structure of Listeria monocytogenes InlP

Released:
DOI: 10.2210/pdb5hl3/pdb
PDB entry 5hl3 coloured by chain, front view.
PDB entry 5hl3 coloured by chain, side view.
PDB entry 5hl3 coloured by chain, top view.
Source organism: Listeria monocytogenes EGD-e
Primary publication:
Listeria monocytogenes InlP interacts with afadin and facilitates basement membrane crossing.
Faralla C, Bastounis EE, Ortega FE, Light SH, Rizzuto G, Gao L, Marciano DK, Nocadello S, Anderson WF, Robbins JR, Theriot JA, Bakardjiev AI
PLoS Pathog 14 e1007094 (2018)
PMID: 29847585

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186940 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Internalin N-terminal domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 361 amino acids
Theoretical weight: 40.58 KDa
Source organism: Listeria monocytogenes EGD-e
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8Y4H2 (Residues: 31-388; Coverage: 100%)
Gene name: lmo2470
Sequence domains:

Ligands and Environments

2 bound ligands:
Ligand CA 8 x CA
Ligand CL 1 x CL
1 modified residue:
Ligand MSE 12 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 21-ID-G
Spacegroup: P41212
Unit cell:
a: 72.883Å b: 72.883Å c: 179.449Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.161 0.16 0.176
Expression system: Escherichia coli BL21(DE3)

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Citations

7 review citations

Infections at the maternal-fetal interface: an overview of pathogenesis and defence.
Megli et al. (2022)
6 more

1 mention without citation

Novel internalin P homologs in Listeria.
Conner et al. (2022)