Function and Biology Details
Biochemical function:
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Inhibin beta A chain (preferred)
PDBe Complex ID:
PDB-CPX-140135 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Inhibin beta A chain
Molecule details ›
Chains: A, C, E, G
Length: 270 amino acids
Theoretical weight: 30.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: TGF-beta propeptide
Length: 270 amino acids
Theoretical weight: 30.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P08476 (Residues: 30-305; Coverage: 62%)
Sequence domains: TGF-beta propeptide
Inhibin beta A chain
Molecule details ›
Chains: B, D, F, H
Length: 116 amino acids
Theoretical weight: 12.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Length: 116 amino acids
Theoretical weight: 12.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P08476 (Residues: 311-426; Coverage: 29%)
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
DIAMOND BEAMLINE I04
Spacegroup:
P31
Expression system: Escherichia coli BL21(DE3)
