Function and Biology Details
Reactions catalysed:
S-adenosyl-L-methionine + a 5'-(5'-triphosphoguanosine)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA]
S-adenosyl-L-methionine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(ribonucleotide)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-(2'-O-methyl-ribonucleotide)-[mRNA]
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
GTP + a 5'-diphospho-[mRNA] = diphosphate + a 5'-(5'-triphosphoguanosine)-[mRNA]
Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
ATP + H(2)O = ADP + phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Papain-like proteinase nsp3 (preferred)
PDBe Complex ID:
PDB-CPX-125702 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Papain-like proteinase nsp3
Molecule details ›
Chain: A
Length: 171 amino acids
Theoretical weight: 18.1 KDa
Source organism: Middle East respiratory syndrome-related coronavirus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Macro domain
Structure domains: Leucine Aminopeptidase, subunit E, domain 1
Length: 171 amino acids
Theoretical weight: 18.1 KDa
Source organism: Middle East respiratory syndrome-related coronavirus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
K9N7C7 (Residues: 1109-1275; Coverage: 2%)
Sequence domains: Macro domain
Structure domains: Leucine Aminopeptidase, subunit E, domain 1
