› 5hsw

X-ray diffraction
3.3Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161014 (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
ORF 37 Chain: A
Molecule details ›
Chain: A
Length: 488 amino acids
Theoretical weight: 55.26 KDa
Source organism: Human herpesvirus 8 type M
Expression system: Escherichia coli
UniProt:
  • Canonical: P88925 (Residues: 1-486; Coverage: 100%)
Sequence domains: Viral alkaline exonuclease
Structure domains: Herpesvirus alkaline exonuclease, N-terminal domain
RNA (5'-R(P*UP*CP*UP*UP*GP*AP*AP*GP*CP*AP*GP*CP*UP*UP*CP*CP*AP*G)-3') Chain: B
Molecule details ›
Chain: B
Length: 31 nucleotides
Theoretical weight: 9.92 KDa
Source organism: Human gammaherpesvirus 8
Expression system: Not provided

Ligands and Environments

1 bound ligand:
Ligand ACT 1 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: C2
Unit cell:
a: 198.2Å b: 45.9Å c: 67.6Å
α: 90° β: 90.1° γ: 90°
R-values:
R R work R free
0.211 0.208 0.262
Expression systems:
  • Escherichia coli
  • Not provided

Quick links

Citations

7 review citations

Structure and mechanism of the Red recombination system of bacteriophage λ.
Caldwell et al. (2019)
6 more

1 mention without citation

KSHV SOX mediated host shutoff: the molecular mechanism underlying mRNA transcript processing.
Lee et al. (2017)