› 5hzr

X-ray diffraction
2.33Å resolution

Crystal structure of MtSnf2

Released:
DOI: 10.2210/pdb5hzr/pdb
PDB entry 5hzr coloured by chain, front view.
PDB entry 5hzr coloured by chain, side view.
PDB entry 5hzr coloured by chain, top view.
Source organism: Thermothelomyces thermophilus ATCC 42464
Primary publication:
Structure of chromatin remodeler Swi2/Snf2 in the resting state.
Xia X, Liu X, Li T, Fang X, Chen Z
Nat Struct Mol Biol 23 722-9 (2016)
PMID: 27399259

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-124286 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
SNF2-family ATP dependent chromatin remodeling factor like protein Chain: A
Molecule details ›
Chain: A
Length: 732 amino acids
Theoretical weight: 84.55 KDa
Source organism: Thermothelomyces thermophilus ATCC 42464
Expression system: Escherichia coli
UniProt:
  • Canonical: G2QDW1 (Residues: 445-1176; Coverage: 50%)
Gene name: MYCTH_115909
Sequence domains:

Ligands and Environments

3 bound ligands:
Ligand KH2 4 x KH2
Ligand NA 1 x NA
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL17U
Spacegroup: C2221
Unit cell:
a: 122.613Å b: 144.266Å c: 121.29Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.195 0.194 0.213
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes.
Clapier et al. (2017)
6 more

9 mentions without citation

Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers.
Hodges et al. (2018)
8 more