› 5i1d

X-ray diffraction
2Å resolution

CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-23/IGKV4-1

Released:
DOI: 10.2210/pdb5i1d/pdb
Model geometry
Fit model/data
PDB entry 5i1d coloured by chain, front view.
PDB entry 5i1d coloured by chain, side view.
PDB entry 5i1d coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural diversity in a human antibody germline library.
Teplyakov A, Obmolova G, Malia TJ, Luo J, Muzammil S, Sweet R, Almagro JC, Gilliland GL
OpenAccess logo MAbs 8 1045-63
PMID: 27210805

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-230478 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
FAB LIGHT CHAIN Chains: A, L
Molecule details ›
Chains: A, L
Length: 220 amino acids
Theoretical weight: 24.23 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
FAB HEAVY CHAIN Chains: B, H
Molecule details ›
Chains: B, H
Length: 228 amino acids
Theoretical weight: 24.15 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: RIGAKU MICROMAX-007 HF
Spacegroup: P212121
Unit cell:
a: 62.71Å b: 111Å c: 159.99Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.216 0.216 0.251
Expression system: Homo sapiens

Quick links

Citations

9 review citations

Antibody Structure and Function: The Basis for Engineering Therapeutics.
Chiu et al. (2019)
8 more

8 mentions without citation

Impact of the Protein Data Bank on antineoplastic approvals.
Westbrook et al. (2020)
7 more