› 5i2m

X-ray diffraction
2.4Å resolution

CRYSTAL STRUCTURE OF VSV-INDIANA (MUDD-SUMMERS STRAIN) GLYCOPROTEIN UNDER ITS ACIDIC CONFORMATION

Released:
DOI: 10.2210/pdb5i2m/pdb
PDB entry 5i2m coloured by chain, front view.
PDB entry 5i2m coloured by chain, side view.
PDB entry 5i2m coloured by chain, top view.
Source organism: Vesicular stomatitis Indiana virus strain Mudd-Summers
Primary publication:
Crystal structure of the low-pH form of the vesicular stomatitis virus glycoprotein G.
Roche S, Bressanelli S, Rey FA, Gaudin Y
Science 313 187-91 (2006)
PMID: 16840692

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143013 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glycoprotein G Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 422 amino acids
Theoretical weight: 47.34 KDa
Source organism: Vesicular stomatitis Indiana virus strain Mudd-Summers
UniProt:
  • Canonical: P0C2X0 (Residues: 1-422; Coverage: 100%)
Gene name: G
Sequence domains: Rhabdovirus spike glycoprotein
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand PE4 5 x PE4
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: C2221
Unit cell:
a: 71.27Å b: 224.2Å c: 375.74Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.183 0.215

Quick links

Citations

69 review citations

Viral membrane fusion.
Harrison SC. (2008)
68 more

7 mentions without citation

Monomeric Intermediates Formed by Vesiculovirus Glycoprotein during Its Low-pH-induced Structural Transition.
Abou-Hamdan et al. (2018)
6 more