› 5i5n

X-ray diffraction
1.42Å resolution

Crystal Structure of N-terminal Domain of Matrix Protein of Thogoto Virus at Acidic pH.

Released:
DOI: 10.2210/pdb5i5n/pdb
PDB entry 5i5n coloured by chain, front view.
PDB entry 5i5n coloured by chain, side view.
PDB entry 5i5n coloured by chain, top view.
Source organism: Thogoto thogotovirus
Primary publication:
pH-dependent conformational changes of a Thogoto virus matrix protein reveal mechanisms of viral assembly and uncoating.
Yang M, Feng F, Liu Y, Wang H, Yang Z, Hou W, Liang H
J Gen Virol 97 2149-2156 (2016)
PMID: 27411929

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182338 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein ML Chains: A, B
Molecule details ›
Chains: A, B
Length: 154 amino acids
Theoretical weight: 17.22 KDa
Source organism: Thogoto thogotovirus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q80A33 (Residues: 3-151; Coverage: 49%)
Gene name: Segment 6
Sequence domains: Matrix and Matrix long proteins N-terminal

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRF BEAMLINE BL19U1
Spacegroup: P212121
Unit cell:
a: 36.982Å b: 88.353Å c: 88.346Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.177 0.176 0.19
Expression system: Escherichia coli

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Citations

2 review citations

Matrix proteins of enveloped viruses: a case study of Influenza A virus M1 protein.
Kordyukova et al. (2019)
1 more