Function and Biology Details
Reactions catalysed:
Sphingomyelin + H(2)O = N-acylsphingosine + phosphocholine
A phosphatidylcholine + H(2)O = 1,2-diacyl-sn-glycerol + phosphocholine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Sphingomyelin phosphodiesterase (preferred)
PDBe Complex ID:
PDB-CPX-148049 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Sphingomyelin phosphodiesterase
Molecule details ›
Chains: A, B, C
Length: 583 amino acids
Theoretical weight: 65.11 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
Sequence domains:
Length: 583 amino acids
Theoretical weight: 65.11 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
- Canonical:
P17405 (Residues: 49-631; Coverage: 100%)
Sequence domains:
Ligands and Environments
Experiments and Validation Details
X-ray source:
CLSI BEAMLINE 08ID-1
Spacegroup:
I222
Expression system: Cricetulus griseus
