› 5ii6

X-ray diffraction
0.95Å resolution

Crystal structure of the ZP-N1 domain of mouse sperm receptor ZP2 at 0.95 A resolution

Released:
DOI: 10.2210/pdb5ii6/pdb
PDB entry 5ii6 coloured by chain, front view.
PDB entry 5ii6 coloured by chain, side view.
PDB entry 5ii6 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structural Basis of Egg Coat-Sperm Recognition at Fertilization.
Raj I, Sadat Al Hosseini H, Dioguardi E, Nishimura K, Han L, Villa A, de Sanctis D, Jovine L
Cell 169 1315-1326.e17 (2017)
PMID: 28622512

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148882 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Processed zona pellucida sperm-binding protein 2 Chain: A
Molecule details ›
Chain: A
Length: 112 amino acids
Theoretical weight: 12.99 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: P20239 (Residues: 35-138; Coverage: 15%)
Gene names: Zp-2, Zp2, Zpa

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P212121
Unit cell:
a: 39.539Å b: 50.013Å c: 51.751Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.128 0.127 0.145
Expression system: Homo sapiens

Quick links

Citations

8 review citations

Find and fuse: Unsolved mysteries in sperm-egg recognition.
Bianchi et al. (2020)
7 more

4 mentions without citation

Mammalian egg coat modifications and the block to polyspermy.
Fahrenkamp et al. (2020)
3 more