Function and Biology Details
Reactions catalysed:
2 6,7-dimethyl-8-(1-D-ribityl)lumazine = riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine
2-dehydro-3-deoxy-6-phosphate-D-gluconate = pyruvate + D-glyceraldehyde 3-phosphate
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero 120-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-107707 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Riboflavin synthase
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, M, O, Q, S
Length: 156 amino acids
Theoretical weight: 17.25 KDa
Source organism: Methanocaldococcus jannaschii DSM 2661
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: 6,7-dimethyl-8-ribityllumazine synthase
Structure domains: Lumazine/riboflavin synthase
Length: 156 amino acids
Theoretical weight: 17.25 KDa
Source organism: Methanocaldococcus jannaschii DSM 2661
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q58584 (Residues: 1-156; Coverage: 100%)
Sequence domains: 6,7-dimethyl-8-ribityllumazine synthase
Structure domains: Lumazine/riboflavin synthase
2-dehydro-3-deoxy-phosphogluconate aldolase
Molecule details ›
Chains: 1, 2, 3, 4, L, N, P, R, T, U, V, W, X, Y, Z
Length: 219 amino acids
Theoretical weight: 23.15 KDa
Source organism: Vibrionales bacterium SWAT-3
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: KDPG and KHG aldolase
Structure domains: Aldolase class I
Length: 219 amino acids
Theoretical weight: 23.15 KDa
Source organism: Vibrionales bacterium SWAT-3
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: A5KUH7 (Residues: 1-209; Coverage: 100%)
Sequence domains: KDPG and KHG aldolase
Structure domains: Aldolase class I
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 24-ID-C
Spacegroup:
I222
Expression system: Escherichia coli BL21(DE3)
