› 5imu

X-ray diffraction
1.9Å resolution

A fragment of conserved hypothetical protein Rv3899c (residues 184-410) from Mycobacterium tuberculosis

Released:
DOI: 10.2210/pdb5imu/pdb
Model geometry
Fit model/data
PDB entry 5imu coloured by chain, front view.
PDB entry 5imu coloured by chain, side view.
PDB entry 5imu coloured by chain, top view.
Source organism: Mycobacterium tuberculosis H37Rv
Primary publication:
Crystal structure of Rv3899c(184-410), a hypothetical protein from Mycobacterium tuberculosis.
Liu Y, Gao Y, Li D, Fleming J, Li H, Bi L
Acta Crystallogr F Struct Biol Commun 72 642-5 (2016)
PMID: 27487929

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126479 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tat (Twin-arginine translocation) pathway signal sequence containing protein Chain: A
Molecule details ›
Chain: A
Length: 227 amino acids
Theoretical weight: 24.25 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O05446 (Residues: 184-410; Coverage: 55%)
Gene name: Rv3899c
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand K 1 x K
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: RIGAKU
Spacegroup: P212121
Unit cell:
a: 50.155Å b: 54.973Å c: 75.807Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.161 0.16 0.19
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 mentions without citation

The crystal structure of the EspB-EspK virulence factor-chaperone complex suggests an additional type VII secretion mechanism in Mycobacterium tuberculosis.
Gijsbers et al. (2023)
1 more