5it2

X-ray diffraction
1.7Å resolution

Structure of a transglutaminase 2-specific autoantibody 693-10-B06 Fab fragment

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-235461 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
heavy chain Chain: H
Molecule details ›
Chain: H
Length: 227 amino acids
Theoretical weight: 24.36 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins
light chain Chain: L
Molecule details ›
Chain: L
Length: 215 amino acids
Theoretical weight: 23.53 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P212121
Unit cell:
a: 74.592Å b: 63.383Å c: 104.811Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.186 0.185 0.204
Expression system: Homo sapiens